CLINICAL NEWS
When asked whether these childhood
ALL survivors could benefit from
participating in widely available exercise
programs (such as gyms or group
classes) as adults, Dr. Ness stressed that
“exercise prescription should be tailored
to accommodate the specific needs of
each survivor so that he or she can be not
only safe, but successful, when starting
to exercise. All exercise should be tailored
to capacity and interests.”
While Dr. Ness’ group did not assess
the psychosocial well-being of these
patients, other data have shown risks
for depression, poor sleep, and poor
quality of life among childhood ALL
survivors. Dr. Ness concurred that these
emotional factors can influence levels
of physical activity, so they should
be taken into consideration when
designing a fitness intervention.
In the near future, her group intends
to conduct further studies about the
effects of dietary protein intake on lean
Comparison of Mean Body Composition and Energy
Balance Among ALL Survivors by CRT Exposure
TABLE 2.
No CRT (A)
CRT (B)
Control (C)
p values
A vs. B
p values
B vs. C
Mean height
163.9 cm
158 cm
164.2 cm
p<0.001
p<0.001
Mean weight
71.1 kg
p=0.01
p=0.07
FEMALES
Mean BMI
26.4 kg/m
81.2 kg
74.9 kg
32.3 kg/m
27.8 kg/m
p<0.001
p<0.001
172.9 cm
2
178.9 cm
p=0.003
p<0.001
p=0.09
p=0.39
p=0.62
p=0.12
2
2
MALES
Mean height
176.1 cm
Mean weight
87.7 kg
Mean BMI
87.8 kg
28.8 kg/m
2
87.3 kg
28.4 kg/m
2
27.2 kg/m
2
T:7”
4.2 Allergic Reactions
REVLIMID is contraindicated in patients who have demonstrated
hypersensitivity (e.g., angioedema, Stevens-Johnson syndrome, toxic
epidermal necrolysis) to lenalidomide [see Warnings and Precautions
(5.8)].
5.2 REVLIMID REMS™ Program
Because of the embryo-fetal risk [see Warnings and Precautions (5.1)],
REVLIMID is available only through a restricted program under a Risk
Evaluation and Mitigation Strategy (REMS), the REVLIMID REMS™
program (formerly known as the “RevAssist®” program).
Required components of the REVLIMID REMS™ program include the
following:
• Prescribers must be certified with the REVLIMID REMS™ program by
enrolling and complying with the REMS requiremen