ASH Clinical News May 2015 | Page 13

ASH | On Demand www.ashondemand.org teachers in histology class, was to help students in introductory courses use the observatory’s telescopes to find an assigned list of astronomical objects: a planet, a nebula, a galaxy, and so on. After the observatory closed at night, I could do my own research in spectroscopy, and I often got so involved in what I was measuring David Steensma, MD, is senior that I lost track of time and was physician at the Dana-Farber surprised to see a pre-dawn glow Cancer Institute and associate in the East. professor of medicine at Harvard Since this was Western MichiMedical School in Boston, MA. gan, lake-effect clouds and poor visibility meant that most winter nights the observatory closed up, and I learned that an empty observatory is also a great place to study or, alternatively, to hang out with girls and conduct other types of research. The sense of wonder that I saw in most of the students who came to the observatory was the same jaw-dropping awe that I felt when I first saw that amazing eosinophil. Not a night went by without at least one, “Wow!” or “Holy cow!” or “Awesome!” from a person looking into an eyepiece. (And sometimes a “Dude, that is totally radical!” – it was the 1980s after all). One student memorably burst into tears the first time she saw the spectacular M57 Ring Nebula in the constellation Lyra. “I’ve had such a bad day, but now, looking at that, it all seems like nothing,” she said, echoing sentiments Tennyson described in his poem “Vastness” a century earlier: What is it all but a trouble of ants in the gleam of a million million of suns? Morphology is still central to hematology, but it is losing primacy. In this age of flow cytometry and molecular genetics, we’ve come to distrust the meaning of cells that we see with eyes aided only by a lens. It is still important to look for eosinophils, but when the blood teems with too many of them, it is equally critical to know whether their presence is accompanied by an imatinib-sensitive rearrangement of the platelet-derived growth factor receptor. I still enjoy sitting at the multi-headed microscope and bringing students to come look at slides. Last month, when I was attending on a hospital service, the residents, students, [