ASH Clinical News March 2016 | Page 19

CLINICAL NEWS The Problem with Positive Thinking Since 1974, the frequency of positive-sounding words has increased almost nine-fold in the titles and abstracts of published papers, according to a “text-mining” analysis of abstracts in PubMed. Over this 40-year period, the use of words like amazing, novel, unprecedented, and innovative rose from 2% in 19741980 to 17.5% in 2014. novel unprecedented amazing innovative Pay-for-Delay on the Way Out? Branded drug companies reached far fewer pay-for-delay deals with generic drug makers in 2014, reversing a steady increase that persisted from 2005 to 2012. 2012: 40 The use of negative words (such as disappointing, pessimistic, discouraging, and unacceptable) also increased – to a lesser degree: 1.3% to 2.4%. (a record high) “The findings fit our own observations that in order to get published, you need to emphasize what is special and unique about your study,” the authors wrote. “If everything is ‘robust’ and ‘novel,’ then there is no distinction between the qualities of findings.” Source: Vinkers CH, Tijdnk JT, Otte WM. Use of positive and negative words in scientific PubMed abstracts between 1974 and 2014: retrosp