ASH Clinical News March 2015 | Page 50

Introducing the first and FDA-approved treatment patients with polycythemia vera an inadequate response to or are In a phase 3 trial of JakafiĀ® (ruxolitinib) vs best available therapy: 21% of patients receiving Jakafi achieved the primary composite end point of hematocrit (Hct) control and spleen volume reduction compared with <1% of patients on best available therapy at week 32 (P < 0.0001)* Indications and Usage Jakafi is indicated for treatment of patients with polycythemia vera who have had an inadequate response to or are intolerant of hydroxyurea. Important Safety Infor