ASH Clinical News March 2015 | Page 25

CLINICAL NEWS Results suggest that prophylactic doses of LMWH should no longer be routinely prescribed for non-thrombophilic women in this clinical setting. “However, because a detrimental effect of aspirin could not be ruled out and might explain the lack of efficacy of the combination with LMWH, it was important to investigate the effect of LMWH alone – as we did in our study,” she added. ● References • Pasquier E, de Saint Martin L, Bohec C, et al. Enoxaparin for prevention of unexplained recurrent miscarriage: a multicenter randomized double-blind placebo-controlled trial. Blood. 2015 January 30. [Epub ahead of print] • Clark P, Walker ID, et al. SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of lowmolecular-weight heparin and low-dose aspirin in women with recurrent miscarriage. Blood. 201 X^H