ASH Clinical News Hematology Pipeline Update: Drug Updates from the | Page 3
FEBRUARY 2016
AMERICAN SOCIETY OF HEMATOLOGY
HEADQUARTERS
2021 L Street NW, Suite 900
Washington, DC 20036
www.hematology.org
Tel: 202-776-0544
EDITOR-IN-CHIEF
Mikkael Sekeres, MD, MS
Vice-Chair for Clinical Research
Director, Leukemia Program
Cleveland Clinic, Taussig Cancer Institute
Cleveland, OH
ASSOCIATE EDITORS
Beth Faiman, CNP, PhD
Cleveland Clinic
Cleveland, OH
Alice Ma, MD
University of North Carolina School of Medicine
Chapel Hill, NC
CONTENTS
David Steensma, MD
Dana-Farber Cancer Institute
Boston, MA
Keith Stewart, MBChB, MBA
Mayo Clinic
Scottsdale, AZ
PUBLISHER
American Medical Communications
EDITORIAL
MANAGING EDITORS
Ariel Jones-DeMaio, AMC
Karen Learner, ASH
ASSOCIATE MANAGING EDITOR
Kerri Fitzgerald, AMC
ART DIRECTOR
Ari Mihos
ASSISTANT ART DIRECTOR
Charlene DePrizio
DIGITAL PROJECTS MANAGER
Chris Gedikli
ADVERTISING
ACCOUNT MANAGER
Nick Luciano
[email protected]
Gene Conselyea
[email protected]
Recruitment advertising orders can be sent to:
DIRECTOR, RECRUITMENT CLASSIFIEDS
Lauren Morgan
[email protected]
©2016 by the American Society of Hematology.
All materials contained in this newsletter are
protected by copyright laws and may not be used,
reproduced, or otherwise exploited in any manner
without the express prior written permission of
ASH Clinical News. Any third-party materials communicated to ASH Clinical News become its copyrighted property and may be used, reproduced, or
otherwise exploited by ASH Clinical News.
FEATURES
BLEEDING DISORDERS
2
ASH/FDA
6
Targeting Antithrombin in
Hemophilia
Joint
Symposium on
Late-Breaking Drug
Approvals
Experts from the U.S. FDA and the
myeloma field review the three new
agents added to the myeloma toolbox in
November 2015: daratumumab, ixazomib,
and elotuzumab.
4
How
Should
Clinicians Be Using
Newly Approved
Drugs in Practice?
In a Special Education Session, malignant
and non-malignant hematologists discuss
how to incorporate three new drugs
into the current treatment algorithms:
Blinatumomab, panobinostat, and
idaruzicumab.
LEUKEMIA
7
Clofarabine in Older Patients
8
Anti-CD33 Antibody in AML
8 ABL001 in TKI-Resistant CML
MYELOMA
15
Panobinostat in TransplantEligible Patients
16
Daratumumab Combo in
RRMM
17
Ixazomib Combo Leads to
Longer PFS in RRMM
All correspondence for the American Society of Hematology should be sent to: American Society of Hematology,
2021 L Street NW, Suite 900, Washington DC 20036.
Neither the American Society of Hematology nor the publisher is responsible for statements made by any editor or contributor. Statements, editorials, or opinions expressed in ASH Clinical News magazine do not necessarily represent official
policy of the American Society of Hematology unless so stated. No responsibility is assumed by the American Society of
Hematology or the Publisher for any injury or damage to persons or property as a matter of product liability, negligence or
otherwise or from any use or operation of any methods, products, instructions or ideas contained in the material herein.
Although all advertising material published in ASH Clinical News magazine is expected to conform to ethical (medical) standards, inclusion in this publication does not constitute a guarantee or endorsement by the American Society
of Hematology or the Publisher of the quality or value of such product or of the claim made of it by its manufacturer.
About the American Society of Hematology
The American Society of Hematology (ASH) is the world’s largest professional society concerned with the causes and
treatments of blood disorders. The mission of the Society is to further the understanding, diagnosis, treatment, and
prevention of disorders affecting the blood, bone marrow, and the immunologic, hemostatic and vascular systems,
by promoting research, clinical care, education, training, and advocacy in hematology.