ASH Clinical News Focus on Rare Diseases | Page 7

KOVALTRY® GIVE HIM THE OPPORTUNITY TO EXPLORE THE POSSIBILITIES The only unmodified, full length rFVIII offering the potential for as few as 2 infusions per week1* INDICATIONS KOVALTRY® Antihemophilic Factor (Recombinant) is a recombinant human DNA sequence derived, full length Factor VIII concentrate indicated for use in adults and children with hemophilia A for: On-demand treatment and control of bleeding episodes Perioperative management of bleeding Routine prophylaxis to reduce the frequency of bleeding episodes KOVALTRY® is not indicated for the treatment of von Willebrand disease. SELECTED IMPORTANT SAFETY INFORMATION KOVALTRY® is contraindicated in patients who have a history of hypersensitivity reactions to the active substance, to any of the excipients, or to mouse or hamster proteins. Please see additional Selected Important Safety Information on following pages. For additional important risk and use information, please see Brief Summary on following pages. *Compared to other rFVIII products.