ASH Clinical News February 2015 | Page 14

Calendar February 28 – March 1 March 12 – 14 April 18 – 22 2015 Highlights of ASH® in Asia National Comprehensive Cancer Network’s 20th Annual Conference 2015 American Association for Cancer Research Annual Meeting Bangkok, Thailand Hollywood, FL The NCCN 20th Annual Conference will gather more than 1,500 oncology professionals to discuss the latest cancer therapies and advancing the standard of cancer care. April 23 – 24 2015 Highlights of ASH® in Latin America Cartagena, Colombia Hear internationally recognized experts analyze the latest updates in hematology research from the ASH Annual meeting. Philadelphia, PA The AACR Annual Meeting 2015 will highlight the latest discoveries in every area of cancer research. This year’s meeting theme is “Bringing Cancer Discoveries to Patients.” Cartagena, Colombia BRIEF SUMMARY: For Full Prescribing Information, see package insert. CONTRAINDICATIONS None. WARNINGS AND PRECAUTIONS Thrombocytopenia, Anemia and Neutropenia Treatment with Jakafi can cause thrombocytopenia, anemia and neutropenia. [see Dosage and Administration (2.1) in Full Prescribing Information]. Manage thrombocytopenia by reducing the dose or temporarily interrupting Jakafi. Platelet transfusions may be necessary [see Dosage and Administration (2.1.1) and Adverse Reactions (6.1) in Full Prescribing Information]. Patients developing anemia may require blood transfusions and/or dose modifications of Jakafi. Severe neutropenia (ANC less than 0.5 X 109/L) was generally reversible by withholding Jakafi until recovery [see Adverse Reactions (6.1)]. Perform a pre-treatment complete blood count (CBC) and monitor CBCs every 2 to 4 weeks until doses are stabilized, and then as clinically indicated. [see Dosage and Administration (2.1.1) and Adverse Reactions (6.1) in Full Prescribing Information]. Risk of Infection Serious bacterial, mycobacterial, fungal and viral infections have occurred. Delay starting therapy with Jakafi until active serious infections have resolved. Observe patients receiving Jakafi for signs and symptoms of infection and manage promptly. Tuberculosis Tuberculosis in fV7F