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CLINICAL NEWS Cancer in Your Own Backyard A recent meta-analysis reviewing lymphoma risk among people exposed to glyphosate-containing herbicides (commonly marketed as Roundup) supported the weed-killer’s carcinogenic potential. A 3D Remedy for SCD? For young patients with sickle cell disease (SCD), taking a virtual trip to a “relaxing underwater world” could help lower pain levels and complement other therapies, according to a small study published in Pediatric Blood & Cancer. Authors examined epidemiologic studies published between 2001 and 2018, finding that people routinely exposed to the herbicide had a 41% higher risk of developing non- Hodgkin lymphoma, compared with nonexposed people. In the study, patients who were hospitalized for vaso- occlusive pain episodes ranked the intensity of their pain on a scale of 1 to 10 before and after a short, immersive virtual reality (VR) session. After the VR session, pain intensity dropped, from a median of 7.3 points to 5.8 points. While they found a “compelling link” between herbicide exposure and cancer, the authors noted that more well-designed, robust studies about appropriate exposure levels are needed. Source: Zhang Rana I, Shaffer RM, et al. Exposure to glyphosate-based herbicides and risk for non-Hodgkin lymphoma: a meta- analysis and supporting evidence. Mutat Res/Rev Mutat Res. 2019 February 10. [Epub ahead of print] 8 7 6 Paperwork Over Patients Despite efforts by the Centers for Medicare & Medicaid Services to reduce doctors’ regulatory burden, many are still buried under paperwork, according to a report from the Medical Group Management Association. In a survey of 426 group practices, 86 % said that the overall regulatory burden increased over the last 12 months. 5 When respondents were asked what aspects of the health-care system increased their regulatory burden, the most common answers were: the Merit-based Incentive Payment System 88 % prior authorization 82 % lack of electronic health record interoperability 80 % Pain was also less extensive: The number of affected body areas decreased from 3 to 2. (P values for all comparisons were p≤0.01.) There were no reported side effects, and all patients requested another VR trip in the future, suggesting that patients enjoyed this pain management option. Source: Agrawal AK, Robertson S, Litwin L, et al. Virtual reality as complementary pain therapy in hospitalized patients with sickle cell disease. Ped Blood Cancer. 2019;66:e27525. Source: Medical Group Management Association. “MGMA 2018 Regulatory Burden Survey.” ASHClinicalNews.org ASH Clinical News 19