ASH Clinical News ACN_4.7_FULL_ISSUE_DIGITAL | Page 38

BACK of the BOOK Heard in the Blogosphere Choosing Between Saving Lives and Saving a Fortune “To understand something about the spiraling cost of health care in the United States, we might begin with a typical conundrum: … Should [a] doctor prescribe the best possible medicine, assuming that [a patient] has private health insurance that will pay the bulk of the costs? Or should [the doctor] try to conserve health-care costs by prescribing the cheaper medicine that is nearly as good? … What can an individual doctor do to fix health-care costs? … [One way is] by deploying powerful tools that are newly at our disposal – genetics, epidemiology, computational analysis, biochemistry. … The big hope, yet unfulfilled, is that such treatment will ultimately increase value and decrease overall cost. It’s the sort of medicine that might treat medicine’s cost crisis.” —Siddhartha Mukherjee, MD, DPhil, on the cost-value conundrum in American health care, in The New York Times Are Cancer Centers “Selling Out” With Clinical Trials Advertising? ASH @ASH_hematology Thank you to all of the members of our Committee on Practice who joined us on Capitol Hill today to #Fight4Hematology and advocate for tools that will help us #ConquerSCD! Ade Adamson, MD @AdeAdamson I bet MOST 4th year medical students could not correctly define all of the following terms: 1) health-care premium 2) health-plan deductible 3) out-of-pocket maximum 4) co-insurance They could probably tell you the genetic mutation in Marfan syndrome though. #meded #priorities Gavin Preston, MD @GavinPrestonMD Second law of #medicine=No one cares how much you know, until they know how much you care. #Ethics Craig Hofmeister, MD, MPH @EagleMyeloma 7 a.m. meeting with a focus on burnout. Many clinicians logged into EHR approving orders, adding attestations... “One of the ways [cancer treatment centers] compete for patients is by offering a menu of clinical-trial options and suggesting that participating in such trials gives patients an edge in their care. … The most insidious aspect of these ads stems from the implication that patients who get access to drugs in trials have an advantage over patients who do not. If that was true, there would be no point in running clinical trials. … Local ethics committees work hard to help patients who are navigating a labyrinth of fear, uncertainty, and hype to see clinical trials for what they are: Medical experiments that play an essential role in generating evidence for the care of future patients. … Patients who offer their bodies to help discover tomorrow’s treatments deserve messages that are truthful, balanced, and respectful of their role in advancing science, not the hype for clinical trials that is becoming increasingly common.” —Jonathan Kimmelman, PhD, and Alex John London, PhD, on the ethics of clinical-trials advertising in STAT News Why We May Lose Generic Drugs Generic drugs account for more than 90 percent of U.S. prescriptions, but manufacturers are worried that slim profit margins will force them to stop making certain medications. In Bloomberg Businessweek, pharma experts describe the coming of the “generic apocalypse.” “We’re one of the companies that continues to make antibiotics, and we’ve asked ourselves for years why we continue to still make them.” —Brendan O’Grady, executive vice president of Teva Pharmaceutical Industries in North America Follow ASH and ASH Clinical News on: @ASH_Hematology, @BloodJournal, @BloodAdvances, and @ASHClinicalNews Facebook.com/AmericanSocietyofHematology @ASH_Hematology 36 ASH Clinical News “We have supported the [drug-buying] consortiums to the point where we’re discontinuing products and shut- ting facilities. … We are not in the position to provide more price reductions. Already this year, [we have] had requests for six different products. ‘Can you make A, B, C?’ The answer is no. And even if we could, pricing is still so low we wouldn’t be able to bring back a product.” —Paul Campanelli, president and chief executive officer of Endo Pharmaceuticals “For many complex reasons, generic drug manufacturers are being challenged to become more efficient and institute more nimble supply chains. The notion that group-purchasing organizations are somehow to blame for generic drugmakers’ woes is a red herring.” —Janine Burkett, RPh, MBA, president of Econdisc and vice president and chief drug sourcing officer at Express Scripts “We constantly talk about the portfolio of the business erod- ing in price. And yet we’re getting these new bills about being price gougers. … The question becomes ultimately how many [generic manufacturers] are going to exit [the market], and where will the market find a new equilibrium?” —Robert Matsuk, president of Glenmark Pharmaceuticals in North America June 2018