ASH Clinical News ACN_4.4_FULL_ISSUE_DIGITAL | Page 16

Data Stream A World of Difference Though more patients are surviving longer after a cancer diagnosis, survival varies widely based on where patients live, according to research published in The Lancet. The authors reviewed 5-year survival rates among 37 million patients who were diagnosed with one of 18 cancer types between 2000 and 2014 and found widespread disparities. For instance, the highest and lowest survival rates for some common cancers were: breast cancer: 90 % in the U.S. and % 66 in India “Governments must recognize population-based cancer registries as key policy tools that can be used to evaluate both the impact of cancer prevention strategies and the effectiveness of health systems for all patients diagnosed with cancer,” the authors concluded. Source: Allemani C, Matsuda T, Di Carlo V, et al. Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries. Lancet. 2018 January 30. [Epub ahead of print] gastrointestinal cancers: pediatric acute lymphocytic leukemia: 68% in South Korea and 33% in the U.S. 95 % in Finland and 50 % in Ecuador The End of an Era? Results from a Gallup survey show that the number of uninsured Americans increased during 2017, putting an end to years of steady decreases following the passage of the Affordable Care Act in 2010. 15% At the end of 2017, 12.2% of U.S. At the end of 2016, adults lacked 10.9% of U.S. health insurance. adults lacked health insurance. 10% Banking on Gene Editing The National Institutes of Health (NIH) is going all in on gene editing, pledging millions in funds to researchers who are improving and adopting these technologies. With its new Somatic Cell Genome Editing program, NIH is investing $ 190 million over 6 years in researchers who are improving the delivery of or developing new gene-editing technologies. The goal is to assemble a “genome-editing toolkit” that can be shared with the larger scientific community. “Genome-editing technologies such as CRISPR/Cas9 are revolutionizing biomedical research,” said NIH Director Francis S. Collins, MD, PhD. “The focus of the Somatic Cell Genome Editing program is to dramatically accelerate the translation of these technol- ogies to the clinic for treatment of as many genetic diseases as possible.” 5% 0% Source: National Institutes of Health press release, January 23, 2018. The increase of 1.3 percentage points translates to 3.2 million Americans who lost health coverage last year. Source: Gallup-Sharecare Well-Being Index, January 16, 2018. 14 ASH Clinical News March 2018