ASH Clinical News ACN_4.3_FULL-ISSUE-DIGITAL | Page 47

CLINICAL NEWS constraints – Najibah A. Galadanci, MD, from the Departments of Hematology and Blood Transfusion at the Bayero University/ Aminu Kano Teaching Hospital in Kano, Nigeria, and colleagues established small, three-member stroke-prevention teams at tertiary-care hospitals in the area. Each stroke-prevention team consisted of a pediatrician, nurse, and radiologist. Team members were trained in National Heart, Lung, and Blood Institute sickle cell disease (SCD) management guidelines – adapted for medical care in low-resource settings – and a pediatric neurologist provided instructions on how to detect a stroke and stroke-related comorbidities. Each clinic was also staffed with a trained multidisciplinary team and a certified radiologist to conduct transcranial doppler ultrasound (TCD) screening. With support from international partners in the United Kingdom and the United States, the teams were trained and installed at four tertiary-care hospitals in Nigeria in January 2017. Since then, 1,249 children with SCA have been screened us- ing TCD. Most were referred to a clinical trial, and of the 7 pe